Prediction Model for Timing of Death in Potential Donors After Circulatory Death (DCD III): Protocol for a Multicenter Prospective Observational Cohort Study
نویسندگان
چکیده
منابع مشابه
Time to death after withdrawal of treatment in donation after circulatory death (DCD) donors.
PURPOSE Controlled donation after circulatory death (DCD) donors make an important contribution to organ transplantation but there is considerable scope for further increasing the conversion of potential to actual DCD organ donors. The period between withdrawal of life-supporting treatment and death (the withdrawal period) is a major determinant of whether organ donation proceeds and it is ther...
متن کاملEstimated supply of organ donors after circulatory determination of death: a population-based cohort study.
1. Grady C. Do IRBs protect human research participants? JAMA. 2010;304 (10):1122-1123. 2. Bledsoe C, Sherin B, Galinsky A, et al. Regulating creativity: research and survival in the IRB iron cage. Northwest Univ Law Rev. 2007;101(2):593-641. 3. Report of independent panel reviewing the University of Pennsylvania’s Institute for Human Gene Therapy. University of Pennsylvania Almanac. http://www...
متن کاملMass Spectrometry Based Metabolomics Comparison of Liver Grafts from Donors after Circulatory Death (DCD) and Donors after Brain Death (DBD) Used in Human Orthotopic Liver Transplantation
Use of marginal liver grafts, especially those from donors after circulatory death (DCD), has been considered as a solution to organ shortage. Inferior outcomes have been attributed to donor warm ischaemic damage in these DCD organs. Here we sought to profile the metabolic mechanisms underpinning donor warm ischaemia. Non-targeted Fourier transform ion cyclotron resonance (FT-ICR) mass spectrom...
متن کاملPrediction of potential for organ donation after cardiac death in patients in neurocritical state: a prospective observational study.
BACKGROUND Successful donation of organs after cardiac death (DCD) requires identification of patients who will die within 60 min of withdrawal of life-sustaining treatment (WLST). We aimed to validate a straightforward model to predict the likelihood of death within 60 min of WLST in patients with irreversible brain injury. METHODS In this multicentre, observational study, we prospectively e...
متن کاملA Modified, Rapid and Safe Technique of Kidney Only Procurement from Donors after Circulatory and Brain Death (DCD, DBD)
There is currently a lack of standard kidney-only procurement technique. Known techniques such as kidney-only procurement using the standard multi-organ procurement technique could potentially cause more iatrogenic injuries due to less adequate exposure. An alternative using the live open kidney donation technique could also be less than ideal due to prior unknown anatomical variation and poten...
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ژورنال
عنوان ژورنال: JMIR Research Protocols
سال: 2020
ISSN: 1929-0748
DOI: 10.2196/16733